Charcot Marie Tooth Disease

In order to communicate information between nervus cellphones, galvanizing signals are sent down long affection pathways c tot whollyyed axones. To speed up the process of sending this information, the axon is insulated by myelin which is produced by another type of cell called the Schwann cell. (2, 6, 7) myeline twists around the axon and prevents the diversion of any electrical signal, render figure 1. Nerve cells are futile to move point muscles without an intact axon and myelin sheath. They are as well as unable to resend sensory information from the limbs back to the brain.(2, 6) Charcot Marie Tooth disorder is caused by a summercater in the factors that make the protein responsible for the structure and/ or function of the axon and myelin sheath. In 1886, Professor blue jean Martin Charcot of France, see figure 2, and his student Pierre Marie published the offset description of distal muscle weakness in the legs and called it peroneal muscular atrophy. (13) Later, Henry Howard Henry Tooth attributed the symptoms described by Charcot and Marie to neuropathy which is a defect in the nerves. (13) Charcot Marie Tooth Disease is caused by a transmutation within one of our agents and it can happen to any cultural group and affects 1 out of every 3, 300 fire hydrant worldwide.

(3) Mutations within our genes are inherited and each of us carries two copies of each gene, one from each parent. There are much forms of Charcot Marie Tooth (CMT) malady; however, the one focused on for this research motif is CMT1A. (3, 6, 9) There are three main types of CMT1, which are all caused by abnormalities in the myelin sheath found on th e neurons of the peripheral nerves. CMT1A is! an autosomal dominant disease. An autosomal dominant disease means that only one copy of the abnormal gene is needed in order to have the disease. (2) CMT1A is caused by genomic plain on chromosome 17, see figure 3. The Duplication is caused by an pitiable meiotic crossover resulting from homologous sequences near the duplicated region....If you want to be possessed of a full essay, order it on our website: OrderEssay.net

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